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JWH-018 also known as(1-pentyl-3-(1-naphthoyl)indole), is a synthetic cannabinoid research chemical, and EZRC are the first to stock.

It is an carbazole based cannabinoid that is the carbazole analogue of JWH-018 and so is perfect for researchers in countries where other cannabinoids are controlled. Like chemicals such as THJ-018 and AB-PINACA, it has relatively low in-vitro CB1/CB2 activity but is still interesting for researchers who like to study that type of synthetic cannabinoid. Buy JWH-250 Online

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Scientists can conduct experiments to determine the basic data on the material, such as melting points, and solublities etc. and see how it compares and contrasts with the data from similar chemicals.

EZRC stock EG-018 in the form of a off-white, high purity powder.

JWH-018 (1-pentyl-3-(1-naphthoyl)indole) or AM-678is an analgesic  chemical. From the naphthoylindole family that acts as a full agonist  at both the CB₁ and CB₂ cannabinoid receptors, with some selectivity for CB₂.  It produces effects in animals similar to those of tetrahydrocannbinol (THC). A cannabinoid naturally present in cannabis. Leading to its use in synthetic cannabis  products such as “legal cannabis herbal incense blends” which in some countries are sold legally as “incense”, labeled “not for human. Buy JWH-250 Online

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JWH-018 is a full agonist of both the CB₁ and CB₂ cannabinoid receptors. With a reported binding affinity of 9.00 ± 5.00 nM at CB₁ and 2.94 ± 2.65 nM at CB₂. JWH-018 has an EC50  of 102 nM for human CB₁ receptors, and 133 nM for human CB₂ receptors. JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, suggesting potent cannabinoid-like activity.

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